Phosphorylation and Dephosphorylation of Beta-Amyloid Peptide in Model Cell Cultures: The Role of Cellular Protein Kinases and Phosphatases

Phosphorylation of beta-amyloid peptide (Aβ) at the Ser8 residue affects its neurotoxicity, metal-dependent oligomerisation, amyloidogenicity, and other pathogenic properties. Phosphorylated Aβ (pS8-Aβ) was detected in vivo in AD model mice and in the brains of patients with AD. However, the pS8-Aβ...

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Detalles Bibliográficos
Autores principales: Barykin, Evgeny P., Yanvarev, Dmitry V., Strelkova, Maria A., Valuev-Elliston, Vladimir T., Varshavskaya, Kseniya B., Mitkevich, Vladimir A., Makarov, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863727/
https://www.ncbi.nlm.nih.gov/pubmed/36676097
http://dx.doi.org/10.3390/life13010147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863727/
https://www.ncbi.nlm.nih.gov/pubmed/36676097
http://dx.doi.org/10.3390/life13010147

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