CX08005, a Protein Tyrosine Phosphatase 1B Inhibitor, Attenuated Hepatic Lipid Accumulation and Microcirculation Dysfunction Associated with Nonalcoholic Fatty Liver Disease

Nonalcoholic fatty liver disease (NAFLD) is one of the common metabolic diseases characterized by hepatic lipid accumulation. Insulin resistance and microcirculation dysfunction are strongly associated with NAFLD. CX08005, an inhibitor of PTP1B with the IC(50) of 0.75 ± 0.07 μM, has been proven to d...

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Detalles Bibliográficos
Autores principales: Li, Jiang, Zhang, Xiaolin, Tian, Jinying, Li, Juan, Li, Xuechen, Wu, Song, Liu, Yuying, Han, Jingyan, Ye, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863901/
https://www.ncbi.nlm.nih.gov/pubmed/36678603
http://dx.doi.org/10.3390/ph16010106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863901/
https://www.ncbi.nlm.nih.gov/pubmed/36678603
http://dx.doi.org/10.3390/ph16010106

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