Liposomal Delivery of Saquinavir to Macrophages Overcomes Cathepsin Blockade by Mycobacterium tuberculosis and Helps Control the Phagosomal Replicative Niches

Mycobacterium tuberculosis is able to establish a chronic colonization of lung macrophages in a controlled replication manner, giving rise to a so-called latent infection. Conversely, when intracellular bacteria undergo actively uncontrolled replication rates, they provide the switch for the active...

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Detalles Bibliográficos
Autores principales: Pires, David, Mandal, Manoj, Pinho, Jacinta, Catalão, Maria João, Almeida, António José, Azevedo-Pereira, José Miguel, Gaspar, Maria Manuela, Anes, Elsa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863908/
https://www.ncbi.nlm.nih.gov/pubmed/36674655
http://dx.doi.org/10.3390/ijms24021142

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9863908/
https://www.ncbi.nlm.nih.gov/pubmed/36674655
http://dx.doi.org/10.3390/ijms24021142

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