Novel Black Seed Polysaccharide Extract-g-Poly (Acrylate) pH-Responsive Hydrogel Nanocomposites for Safe Oral Insulin Delivery: Development, In Vitro, In Vivo and Toxicological Evaluation

Oral delivery of insulin has always been a challenging task due to harsh gut environment involving variable pH and peptidase actions. Currently, no Food and Drug Administration (FDA) approved oral insulin formulation is commercially available, only intravenous (IV) or subcutaneous (SC) routes. There...

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Detalles Bibliográficos
Autores principales: Shabir, Farya, Mahmood, Asif, Zafar, Nadiah, Zaman, Muhammad, Sarfraz, Rai Muhammad, Ijaz, Hira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864008/
https://www.ncbi.nlm.nih.gov/pubmed/36678691
http://dx.doi.org/10.3390/pharmaceutics15010062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864008/
https://www.ncbi.nlm.nih.gov/pubmed/36678691
http://dx.doi.org/10.3390/pharmaceutics15010062

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