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An Analytical Method for Quantifying the Yields of DNA Double-Strand Breaks Coupled with Strand Breaks by γ-H2AX Focus Formation Assay Based on Track-Structure Simulation

Complex DNA double-strand break (DSB), which is defined as a DSB coupled with additional strand breaks within 10 bp in this study, induced after ionizing radiation or X-rays, is recognized as fatal damage which can induce cell death with a certain probability. In general, a DSB site inside the nucle...

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Detalles Bibliográficos
Autores principales: Yachi, Yoshie, Matsuya, Yusuke, Yoshii, Yuji, Fukunaga, Hisanori, Date, Hiroyuki, Kai, Takeshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864015/
https://www.ncbi.nlm.nih.gov/pubmed/36674901
http://dx.doi.org/10.3390/ijms24021386