Exploring the Pivotal Components Influencing the Side Effects Induced by an Analgesic-Antitumor Peptide from Scorpion Venom on Human Voltage-Gated Sodium Channels 1.4 and 1.5 through Computational Simulation

Voltage-gated sodium channels (VGSCs, or Na(v)) are important determinants of action potential generation and propagation. Efforts are underway to develop medicines targeting different channel subtypes for the treatment of related channelopathies. However, a high degree of conservation across its ni...

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Detalles Bibliográficos
Autores principales: Zhao, Fan, Fang, Liangyi, Wang, Qi, Ye, Qi, He, Yanan, Xu, Weizhuo, Song, Yongbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864070/
https://www.ncbi.nlm.nih.gov/pubmed/36668853
http://dx.doi.org/10.3390/toxins15010033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864070/
https://www.ncbi.nlm.nih.gov/pubmed/36668853
http://dx.doi.org/10.3390/toxins15010033

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