Cis-Allosteric Regulation of HIV-1 Reverse Transcriptase by Integrase

Reverse transcriptase (RT) and integrase (IN) are encoded tandemly in the pol genes of retroviruses. We reported recently that HIV-1 RT and IN need to be supplied as the pol precursor intermediates, in which RT and IN are in fusion form (RTIN) to exert efficient reverse transcription in the context...

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Detalles Bibliográficos
Autores principales: Masuda, Takao, Kotani, Osamu, Yokoyama, Masaru, Abe, Yuya, Kawai, Gota, Sato, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864105/
https://www.ncbi.nlm.nih.gov/pubmed/36680070
http://dx.doi.org/10.3390/v15010031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864105/
https://www.ncbi.nlm.nih.gov/pubmed/36680070
http://dx.doi.org/10.3390/v15010031

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