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Cis-Allosteric Regulation of HIV-1 Reverse Transcriptase by Integrase

Reverse transcriptase (RT) and integrase (IN) are encoded tandemly in the pol genes of retroviruses. We reported recently that HIV-1 RT and IN need to be supplied as the pol precursor intermediates, in which RT and IN are in fusion form (RTIN) to exert efficient reverse transcription in the context...

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Detalles Bibliográficos
Autores principales:	Masuda, Takao, Kotani, Osamu, Yokoyama, Masaru, Abe, Yuya, Kawai, Gota, Sato, Hironori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864105/ https://www.ncbi.nlm.nih.gov/pubmed/36680070 http://dx.doi.org/10.3390/v15010031

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