A Focused Review of Ras Guanine Nucleotide-Releasing Protein 1 in Immune Cells and Cancer

Four Ras guanine nucleotide-releasing proteins (RasGRP1 through 4) belong to the family of guanine nucleotide exchange factors (GEFs). RasGRPs catalyze the release of GDP from small GTPases Ras and Rap and facilitate their transition from an inactive GDP-bound to an active GTP-bound state. Thus, the...

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Detalles Bibliográficos
Autores principales: Hsu, Tu Chun, Rodrigues, Gisele O. L., Winer, Hila, Hixon, Julie A., Li, Wenqing, Tarasova, Nadya I., Durum, Scott K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864139/
https://www.ncbi.nlm.nih.gov/pubmed/36675167
http://dx.doi.org/10.3390/ijms24021652

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864139/
https://www.ncbi.nlm.nih.gov/pubmed/36675167
http://dx.doi.org/10.3390/ijms24021652

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