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Acteoside alleviates UUO-induced inflammation and fibrosis by regulating the HMGN1/TLR4/TREM1 signaling pathway

PURPOSE: Acteoside (Act), a phenylethanoid compound that was first isolated from mullein, has been widely used for the investigation of anti-inflammatory and anti-fibrotic effect. However, the mechanism of Act against unilateral ureteral obstruction (UUO)-mediated renal injury is largely unknown. Th...

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Detalles Bibliográficos
Autores principales: Mao, Yan, Yu, Jiali, Da, Jingjing, Yu, Fuxun, Zha, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864189/
https://www.ncbi.nlm.nih.gov/pubmed/36691481
http://dx.doi.org/10.7717/peerj.14765