DMSO-Induced Unfolding of the Antifungal Disulfide Protein PAF and Its Inactive Variant: A Combined NMR and DSC Study

PAF and related antifungal proteins are promising antimicrobial agents. They have highly stable folds around room temperature due to the presence of 3–4 disulfide bonds. However, unfolded states persist and contribute to the thermal equilibrium in aqueous solution, and low-populated states might inf...

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Detalles Bibliográficos
Autores principales: Czajlik, András, Batta, Ágnes, Kerner, Kinga, Fizil, Ádám, Hajdu, Dorottya, Raics, Mária, Kövér, Katalin E., Batta, Gyula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864379/
https://www.ncbi.nlm.nih.gov/pubmed/36674720
http://dx.doi.org/10.3390/ijms24021208

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864379/
https://www.ncbi.nlm.nih.gov/pubmed/36674720
http://dx.doi.org/10.3390/ijms24021208

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