Afatinib Reverses EMT via Inhibiting CD44-Stat3 Axis to Promote Radiosensitivity in Nasopharyngeal Carcinoma

Background: Afatinib, a second-generation tyrosine kinase inhibitor (TKI), exerts its radiosensitive effects in nasopharyngeal carcinoma (NPC). However, the detailed mechanism of afatinib-mediated sensitivity to radiation is still obscure in NPC. Methods: Quantitative phosphorylated proteomics and b...

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Detalles Bibliográficos
Autores principales: Huang, Huichao, Huang, Fangling, Liang, Xujun, Fu, Ying, Cheng, Zhe, Huang, Yan, Chen, Zhuchu, Duan, Yankun, Chen, Yongheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864417/
https://www.ncbi.nlm.nih.gov/pubmed/36678534
http://dx.doi.org/10.3390/ph16010037

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864417/
https://www.ncbi.nlm.nih.gov/pubmed/36678534
http://dx.doi.org/10.3390/ph16010037

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