Camptothecin Effectively Regulates Germline Differentiation through Bam–Cyclin A Axis in Drosophila melanogaster

Camptothecin (CPT), first isolated from Chinese tree Camptotheca acuminate, produces rapid and prolonged inhibition of DNA synthesis and induction of DNA damage by targeting topoisomerase I (top1), which is highly activated in cancer cells. CPT thus exhibits remarkable anticancer activities in vario...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Jing, Zhang, Shijie, Sun, Zhipeng, Cai, Yu, Zhong, Guohua, Yi, Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864452/
https://www.ncbi.nlm.nih.gov/pubmed/36675143
http://dx.doi.org/10.3390/ijms24021617

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864452/
https://www.ncbi.nlm.nih.gov/pubmed/36675143
http://dx.doi.org/10.3390/ijms24021617

Ejemplares similares