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Camptothecin Effectively Regulates Germline Differentiation through Bam–Cyclin A Axis in Drosophila melanogaster

Camptothecin (CPT), first isolated from Chinese tree Camptotheca acuminate, produces rapid and prolonged inhibition of DNA synthesis and induction of DNA damage by targeting topoisomerase I (top1), which is highly activated in cancer cells. CPT thus exhibits remarkable anticancer activities in vario...

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Detalles Bibliográficos
Autores principales:	Zhang, Jing, Zhang, Shijie, Sun, Zhipeng, Cai, Yu, Zhong, Guohua, Yi, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864452/ https://www.ncbi.nlm.nih.gov/pubmed/36675143 http://dx.doi.org/10.3390/ijms24021617

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