Identification of a Novel Dual Inhibitor of Acetylcholinesterase and Butyrylcholinesterase: In Vitro and In Silico Studies

The enhancement of cholinergic functions via acetylcholinesterase (AChE) and butyrylcholinesterase (BuChE) inhibition is considered a valuable therapeutic strategy for the treatment of Alzheimer’s disease. This study aimed to evaluate the in vitro effect of ZINC390718, previously filtered using comp...

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Detalles Bibliográficos
Autores principales: de Almeida, Raquel B. M., Barbosa, Deyse B., do Bomfim, Mayra R., Amparo, Jéssika A. O., Andrade, Bruno S., Costa, Silvia L., Campos, Joaquín M., Cruz, Jorddy N., Santos, Cleydson B. R., Leite, Franco H. A., Botura, Mariana B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864454/
https://www.ncbi.nlm.nih.gov/pubmed/36678592
http://dx.doi.org/10.3390/ph16010095

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864454/
https://www.ncbi.nlm.nih.gov/pubmed/36678592
http://dx.doi.org/10.3390/ph16010095

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