Therapeutic Targeting of TLR4 for Inflammation, Infection, and Cancer: A Perspective for Disaccharide Lipid A Mimetics

The Toll-like receptor 4 (TLR4) signaling pathway plays a central role in the prompt defense against infectious challenge and provides immediate response to Gram-negative bacterial infection. The TLR4/MD-2 complex can sense and respond to various pathogen-associated molecular patterns (PAMPs) with b...

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Detalles Bibliográficos
Autores principales: Heine, Holger, Zamyatina, Alla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864529/
https://www.ncbi.nlm.nih.gov/pubmed/36678520
http://dx.doi.org/10.3390/ph16010023

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864529/
https://www.ncbi.nlm.nih.gov/pubmed/36678520
http://dx.doi.org/10.3390/ph16010023

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