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Phenotype Switching and the Melanoma Microenvironment; Impact on Immunotherapy and Drug Resistance

Melanoma, a highly heterogeneous tumor, is comprised of a functionally diverse spectrum of cell phenotypes and subpopulations, including stromal cells in the tumor microenvironment (TME). Melanoma has been shown to dynamically shift between different transcriptional states or phenotypes. This is ref...

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Detalles Bibliográficos
Autores principales: Hossain, Sultana Mehbuba, Eccles, Michael R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864717/
https://www.ncbi.nlm.nih.gov/pubmed/36675114
http://dx.doi.org/10.3390/ijms24021601