Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site

Translation initiation of the hepatitis C virus (HCV) mRNA depends on an internal ribosome entry site (IRES) that encompasses most of the 5′UTR and includes nucleotides of the core coding region. This study shows that the polypyrimidine-tract-binding protein (PTB), an RNA-binding protein with four R...

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Detalles Bibliográficos
Autores principales: Angulo, Jenniffer, Cáceres, C. Joaquín, Contreras, Nataly, Fernández-García, Leandro, Chamond, Nathalie, Ameur, Melissa, Sargueil, Bruno, López-Lastra, Marcelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864772/
https://www.ncbi.nlm.nih.gov/pubmed/36680049
http://dx.doi.org/10.3390/v15010008

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864772/
https://www.ncbi.nlm.nih.gov/pubmed/36680049
http://dx.doi.org/10.3390/v15010008

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