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Polypyrimidine-Tract-Binding Protein Isoforms Differentially Regulate the Hepatitis C Virus Internal Ribosome Entry Site
Translation initiation of the hepatitis C virus (HCV) mRNA depends on an internal ribosome entry site (IRES) that encompasses most of the 5′UTR and includes nucleotides of the core coding region. This study shows that the polypyrimidine-tract-binding protein (PTB), an RNA-binding protein with four R...
Autores principales: | Angulo, Jenniffer, Cáceres, C. Joaquín, Contreras, Nataly, Fernández-García, Leandro, Chamond, Nathalie, Ameur, Melissa, Sargueil, Bruno, López-Lastra, Marcelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864772/ https://www.ncbi.nlm.nih.gov/pubmed/36680049 http://dx.doi.org/10.3390/v15010008 |
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