Trifluoromethylated 4,5-Dihydro-1,2,4-triazin-6(1H)-ones via (3+3)-Annulation of Nitrile Imines with α-Amino Esters

The synthesis of two series of monocyclic and bicyclic trifluoromethylated 4,5-dihydro-1,2,4-triazin-6(1H)-one derivatives based on (3+3)-annulation of methyl esters derived from natural α-amino acids with in situ generated trifluoroacetonitrile imines has been described. The devised protocol is cha...

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Detalles Bibliográficos
Autores principales: Kowalczyk, Anna, Świątek, Kamil, Celeda, Małgorzata, Utecht-Jarzyńska, Greta, Jaskulska, Agata, Gach-Janczak, Katarzyna, Jasiński, Marcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864844/
https://www.ncbi.nlm.nih.gov/pubmed/36676595
http://dx.doi.org/10.3390/ma16020856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864844/
https://www.ncbi.nlm.nih.gov/pubmed/36676595
http://dx.doi.org/10.3390/ma16020856

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