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Genetic Iron Overload Hampers Development of Cutaneous Leishmaniasis in Mice

The survival, growth, and virulence of Leishmania spp., a group of protozoan parasites, depends on the proper access and regulation of iron. Macrophages, Leishmania’s host cell, may divert iron traffic by reducing uptake or by increasing the efflux of iron via the exporter ferroportin. This parasite...

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Detalles Bibliográficos
Autores principales: Charlebois, Edouard, Li, Yupeng, Wagner, Victoria, Pantopoulos, Kostas, Olivier, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864902/
https://www.ncbi.nlm.nih.gov/pubmed/36675185
http://dx.doi.org/10.3390/ijms24021669