Short-Chain Fatty Acids Attenuate 5-Fluorouracil-Induced THP-1 Cell Inflammation through Inhibiting NF-κB/NLRP3 Signaling via Glycerolphospholipid and Sphingolipid Metabolism

5-Fluorouracil (5-FU) is a common anti-tumor drug, but there is no effective treatment for its side effect, intestinal mucositis. The inflammatory reaction of macrophages in intestinal mucosa induced by 5-FU is an important cause of intestinal mucositis. In this study, we investigated the anti-infla...

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Detalles Bibliográficos
Autores principales: Zhang, Yanyan, Xi, Yue, Yang, Changshui, Gong, Weijuan, Wang, Chengyin, Wu, Liang, Wang, Dongxu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864921/
https://www.ncbi.nlm.nih.gov/pubmed/36677551
http://dx.doi.org/10.3390/molecules28020494

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864921/
https://www.ncbi.nlm.nih.gov/pubmed/36677551
http://dx.doi.org/10.3390/molecules28020494

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