Functional Characterization of Four Known Cav2.1 Variants Associated with Neurodevelopmental Disorders

Cav2.1 channels are expressed throughout the brain and are the predominant Ca(2+) channels in the Purkinje cells. These cerebellar neurons fire spontaneously, and Cav2.1 channels are involved in the regular pacemaking activity. The loss of precision of the firing pattern of Purkinje cells leads to a...

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Detalles Bibliográficos
Autores principales: Folacci, Mathilde, Estaran, Sébastien, Ménard, Claudine, Bertaud, Anaïs, Rousset, Matthieu, Roussel, Julien, Thibaud, Jean-Baptiste, Vignes, Michel, Chavanieu, Alain, Charnet, Pierre, Cens, Thierry
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864995/
https://www.ncbi.nlm.nih.gov/pubmed/36676903
http://dx.doi.org/10.3390/membranes13010096

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864995/
https://www.ncbi.nlm.nih.gov/pubmed/36676903
http://dx.doi.org/10.3390/membranes13010096

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