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Functional Characterization of Four Known Cav2.1 Variants Associated with Neurodevelopmental Disorders
Cav2.1 channels are expressed throughout the brain and are the predominant Ca(2+) channels in the Purkinje cells. These cerebellar neurons fire spontaneously, and Cav2.1 channels are involved in the regular pacemaking activity. The loss of precision of the firing pattern of Purkinje cells leads to a...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864995/ https://www.ncbi.nlm.nih.gov/pubmed/36676903 http://dx.doi.org/10.3390/membranes13010096 |