Cargando…

Functional Characterization of Four Known Cav2.1 Variants Associated with Neurodevelopmental Disorders

Cav2.1 channels are expressed throughout the brain and are the predominant Ca(2+) channels in the Purkinje cells. These cerebellar neurons fire spontaneously, and Cav2.1 channels are involved in the regular pacemaking activity. The loss of precision of the firing pattern of Purkinje cells leads to a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Folacci, Mathilde, Estaran, Sébastien, Ménard, Claudine, Bertaud, Anaïs, Rousset, Matthieu, Roussel, Julien, Thibaud, Jean-Baptiste, Vignes, Michel, Chavanieu, Alain, Charnet, Pierre, Cens, Thierry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9864995/ https://www.ncbi.nlm.nih.gov/pubmed/36676903 http://dx.doi.org/10.3390/membranes13010096

Ejemplares similares

Xenopus Oocytes: A Tool to Decipher Molecular Specificity of Insecticides towards Mammalian and Insect GABA—A Receptors
por: Bertaud, Anaïs, et al.
Publicado: (2022)

Manipulations of Glutathione Metabolism Modulate IP(3)-Mediated Store-Operated Ca(2+) Entry on Astroglioma Cell Line
por: Mokrane, Nawfel, et al.
Publicado: (2021)

Different efficiency of auxiliary/chaperone proteins to promote the functional reconstitution of honeybee glutamate and acetylcholine receptors in Xenopus laevis oocytes
por: Brunello, Lorène, et al.
Publicado: (2022)

The Glutathione Metabolite γ-Glutamyl-Glutamate Partially Activates Glutamate NMDA Receptors in Central Neurons With Higher Efficacy for GluN2B-Containing Receptors
por: Sebih, Fatiha, et al.
Publicado: (2022)

Molecular Determinant for Specific Ca/Ba Selectivity Profiles of Low and High Threshold Ca(2+) Channels
por: Cens, Thierry, et al.
Publicado: (2007)

Mammalian Brain Ca(2+) Channel Activity Transplanted into Xenopus laevis Oocytes
por: Rousset, Matthieu, et al.
Publicado: (2022)

Honeybee locomotion is impaired by Am-Ca(V)3 low voltage-activated Ca(2+) channel antagonist
por: Rousset, M., et al.
Publicado: (2017)

Biophysical characterization of the honeybee DSC1 orthologue reveals a novel voltage-dependent Ca(2+) channel subfamily: Ca(V)4
por: Gosselin-Badaroudine, Pascal, et al.
Publicado: (2016)

Pyrethroids Differentially Alter Voltage-Gated Sodium Channels from the Honeybee Central Olfactory Neurons
por: Kadala, Aklesso, et al.
Publicado: (2014)

Characterization of the honeybee AmNa(V)1 channel and tools to assess the toxicity of insecticides
por: Gosselin-Badaroudine, Pascal, et al.
Publicado: (2015)

Voltage-gated sodium channels from the bees Apis mellifera and Bombus terrestris are differentially modulated by pyrethroid insecticides
por: Kadala, Aklesso, et al.
Publicado: (2019)

Interleukin 21 (IL-21) regulates chronic allograft vasculopathy (CAV) in murine heart allograft rejection
por: Khattar, Mithun, et al.
Publicado: (2019)

Importance of the Choice of a Recombinant System to Produce Large Amounts of Functional Membrane Protein hERG
por: Vasseur, Lucie, et al.
Publicado: (2019)

Fluorescent analogues of BeKm-1 with high and specific activity against the hERG channel
por: Vasseur, Lucie, et al.
Publicado: (2019)

Functional network dynamics in a neurodevelopmental disorder of known genetic origin
por: Hawkins, Erin, et al.
Publicado: (2019)

Protein expression pattern in cerebellum of Cav2.1 mutant, tottering-6j mice
por: Kim, Tae Yeon, et al.
Publicado: (2016)

Prognostic Value of CAV1 and CAV2 in Head and Neck Squamous Cell Carcinoma
por: He, Jingyu, et al.
Publicado: (2023)

Redetermination of metarossite, CaV(5+) (2)O(6)·2H(2)O
por: Kobsch, Anaïs, et al.
Publicado: (2016)

Ethnic specific association of the CAV1/CAV2 locus with primary open-angle glaucoma
por: Rong, Shi Song, et al.
Publicado: (2016)

Ankyrin B and Ankyrin B variants differentially modulate intracellular and surface Cav2.1 levels
por: Choi, Catherine S. W., et al.
Publicado: (2019)

Clinical and molecular spectrum of P/Q type calcium channel Cav2.1 in epileptic patients
por: Alehabib, Elham, et al.
Publicado: (2021)

Guioa Cav. (Sapindaceae) : taxonomy, phylogeny, and historical biogeography /
por: Welzen, P. C. van
Publicado: (1989)

Functional Exploration Of T-Type Calcium Channels (Cav3.2 And Cav3.3) And Their Sensitivity To Zinc
por: Hazzaz Abouamal, Tahar, et al.
Publicado: (2018)

Post-mortem gene expression of calcium channels Cav1.2 and Cav1.3 in schizophrenia
por: Schmitt, Andrea, et al.
Publicado: (2022)

A CACNA1A variant associated with trigeminal neuralgia alters the gating of Cav2.1 channels
por: Gambeta, Eder, et al.
Publicado: (2021)

Higher scores on autonomic symptom scales in pediatric patients with neurodevelopmental disorders of known genetic etiology
por: DiCriscio, Antoinette S, et al.
Publicado: (2022)

Lack of association of SNP rs4236601 near CAV1 and CAV2 with POAG in a Saudi cohort
por: Abu-Amero, Khaled K., et al.
Publicado: (2012)

Expression-associated polymorphisms of CAV1-CAV2 affect intraocular pressure and high-tension glaucoma risk
por: Kim, Sewon, et al.
Publicado: (2015)

CaV1 and CaV2 calcium channels mediate the release of distinct pools of synaptic vesicles
por: Mueller, Brian D, et al.
Publicado: (2023)

Cav1/EREG/YAP Axis in the Treatment Resistance of Cav1-Expressing Head and Neck Squamous Cell Carcinoma
por: Burgy, Mickaël, et al.
Publicado: (2021)

Global and Local Connectivity Differences Converge With Gene Expression in a Neurodevelopmental Disorder of Known Genetic Origin
por: Bathelt, Joe, et al.
Publicado: (2017)

Estudio fitoquímico de Salvia regla Cav.
por: Hernández Ortiz, Mireya
Publicado: (1986)

Composition and Antidiarrheal Activity of Bidens odorata Cav.
por: Zavala-Mendoza, Daniel, et al.
Publicado: (2013)

Distinct Basal Metabolism in Three Mouse Models of Neurodevelopmental Disorders
por: Menzies, Caitlin, et al.
Publicado: (2021)

The human channel gating–modifying A749G CACNA1D (Cav1.3) variant induces a neurodevelopmental syndrome–like phenotype in mice
por: Ortner, Nadine J., et al.
Publicado: (2023)

Molecular Characterization of an SV Capture Site in the Mid-Region of the Presynaptic CaV2.1 Calcium Channel C-Terminal
por: Snidal, Christine A., et al.
Publicado: (2018)

P/Q Type Calcium Channel Cav2.1 Defines a Unique Subset of Glomeruli in the Mouse Olfactory Bulb
por: Pyrski, Martina, et al.
Publicado: (2018)

Large-scale analyses of CAV1 and CAV2 suggest their expression is higher in post-mortem ALS brain tissue and affects survival
por: Adey, Brett N., et al.
Publicado: (2023)

CavKA(HYBRID) – between hard spheres and Gaussians
por: Koelling, Florian, et al.
Publicado: (2012)

Beam Load Compensation in Cav. no. 7 (ring 1)
por: Frischholz, Hans
Publicado: (1973)

Cannot write session to /tmp/vufind_sessions/sess_eofn1qmfauon2h6if9s0ujpr1r