Cargando…

Structure-Based Design, Synthesis, and Biological Evaluation of the Cage–Amide Derived Orthopox Virus Replication Inhibitors

Despite the fact that the variola virus is considered eradicated, the search for new small molecules with activity against orthopoxviruses remains an important task, especially in the context of recent outbreaks of monkeypox. As a result of this work, a number of amides of benzoic acids containing a...

Descripción completa

Detalles Bibliográficos
Autores principales: Mozhaitsev, Evgenii S., Suslov, Evgeniy V., Rastrepaeva, Daria A., Yarovaya, Olga I., Borisevich, Sophia S., Khamitov, Edward M., Kolybalov, Dmitry S., Arkhipov, Sergey G., Bormotov, Nikolai I., Shishkina, Larisa N., Serova, Olga A., Brunilin, Roman V., Vernigora, Andrey A., Nawrozkij, Maxim B., Agafonov, Alexander P., Maksyutov, Rinat A., Volcho, Konstantin P., Salakhutdinov, Nariman F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865139/
https://www.ncbi.nlm.nih.gov/pubmed/36680072
http://dx.doi.org/10.3390/v15010029