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Expression and Characterization of Intein-Cyclized Trimer of Staphylococcus aureus Protein A Domain Z

Staphylococcus aureus protein A (SpA) is an IgG Fc-binding virulence factor that is widely used in antibody purification and as a scaffold to develop affinity molecules. A cyclized SpA Z domain could offer exopeptidase resistance, reduced chromatographic ligand leaching after single-site endopeptida...

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Detalles Bibliográficos
Autores principales: Nandy, Suman, Maranholkar, Vijay M., Crum, Mary, Wasden, Katherine, Patil, Ujwal, Goyal, Atul, Vu, Binh, Kourentzi, Katerina, Mo, William, Henrickson, Amy, Demeler, Borries, Sen, Mehmet, Willson, Richard C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865183/
https://www.ncbi.nlm.nih.gov/pubmed/36674796
http://dx.doi.org/10.3390/ijms24021281