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Expression and Characterization of Intein-Cyclized Trimer of Staphylococcus aureus Protein A Domain Z
Staphylococcus aureus protein A (SpA) is an IgG Fc-binding virulence factor that is widely used in antibody purification and as a scaffold to develop affinity molecules. A cyclized SpA Z domain could offer exopeptidase resistance, reduced chromatographic ligand leaching after single-site endopeptida...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865183/ https://www.ncbi.nlm.nih.gov/pubmed/36674796 http://dx.doi.org/10.3390/ijms24021281 |