Improvement of the Chemical Reactivity of Michael Acceptor of Ethacrynic Acid Correlates with Antiproliferative Activities

The present study aims to report the design, synthesis, and biological activity of new ethacrynic acid (EA) analogs (6–10) obtained by the double modulation of the carboxylic acid moiety and the aromatic ring with the aim to increase the chemical reactivity of Michael acceptor of EA. All obtained co...

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Detalles Bibliográficos
Autores principales: El Abbouchi, Abdelmoula, El Brahmi, Nabil, Hiebel, Marie-Aude, Ghammaz, Hamza, El Fahime, Elmostafa, Bignon, Jérôme, Guillaumet, Gérald, Suzenet, Franck, El Kazzouli, Saïd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865193/
https://www.ncbi.nlm.nih.gov/pubmed/36677966
http://dx.doi.org/10.3390/molecules28020910

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865193/
https://www.ncbi.nlm.nih.gov/pubmed/36677966
http://dx.doi.org/10.3390/molecules28020910

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