Dapagliflozin Treatment Augments Bioactive Phosphatidylethanolamine Concentrations in Kidney Cortex Membrane Fractions of Hypertensive Diabetic db/db Mice and Alters the Density of Lipid Rafts in Mouse Proximal Tubule Cells

In addition to inhibiting renal glucose reabsorption and allowing for glucose excretion, the sodium/glucose cotransporter 2 (SGLT2) inhibitor dapagliflozin may be efficacious in treating various comorbidities associated with type 2 diabetes mellitus (T2DM). The molecular mechanisms by which dapaglif...

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Detalles Bibliográficos
Autores principales: Gholam, Mohammed F., Liu, Lauren P., Searcy, Louis A., Denslow, Nancy D., Alli, Abdel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865226/
https://www.ncbi.nlm.nih.gov/pubmed/36674924
http://dx.doi.org/10.3390/ijms24021408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865226/
https://www.ncbi.nlm.nih.gov/pubmed/36674924
http://dx.doi.org/10.3390/ijms24021408

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