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No Placebo Effect beyond Regression to the Mean on the Six Minute Walk Test in Pulmonary Arterial Hypertension Trials

In drug studies, patients are often included when the disease activity is high. This will make any treatment appear to lessen disease activity, although the improvement is biased by selection. This effect is known as regression towards the mean (RTM). We aimed at investigating drug trials in Pulmona...

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Detalles Bibliográficos
Autores principales: Anheyer, Dennis, Bugaj, Till Johannes, Lüdtke, Rainer, Appelbaum, Sebastian, Trübel, Hubert, Ostermann, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865257/
https://www.ncbi.nlm.nih.gov/pubmed/36674584
http://dx.doi.org/10.3390/ijms24021069