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No Placebo Effect beyond Regression to the Mean on the Six Minute Walk Test in Pulmonary Arterial Hypertension Trials
In drug studies, patients are often included when the disease activity is high. This will make any treatment appear to lessen disease activity, although the improvement is biased by selection. This effect is known as regression towards the mean (RTM). We aimed at investigating drug trials in Pulmona...
Autores principales: | Anheyer, Dennis, Bugaj, Till Johannes, Lüdtke, Rainer, Appelbaum, Sebastian, Trübel, Hubert, Ostermann, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865257/ https://www.ncbi.nlm.nih.gov/pubmed/36674584 http://dx.doi.org/10.3390/ijms24021069 |
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