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Characterization of Systemic and Mucosal Humoral Immune Responses to an Adjuvanted Intranasal SARS-CoV-2 Protein Subunit Vaccine Candidate in Mice

Continuous viral evolution of SARS-CoV-2 has resulted in variants capable of immune evasion, vaccine breakthrough infections and increased transmissibility. New vaccines that invoke mucosal immunity may provide a solution to reducing virus transmission. Here, we evaluated the immunogenicity of intra...

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Detalles Bibliográficos
Autores principales: Maltseva, Mariam, Galipeau, Yannick, Renner, Tyler M., Deschatelets, Lise, Durocher, Yves, Akache, Bassel, Langlois, Marc-André
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865305/
https://www.ncbi.nlm.nih.gov/pubmed/36679875
http://dx.doi.org/10.3390/vaccines11010030