Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants

The KCNQ1 gene encodes the α-subunit of the cardiac voltage-gated potassium (Kv) channel KCNQ1, also denoted as Kv7.1 or KvLQT1. The channel assembles with the ß-subunit KCNE1, also known as minK, to generate the slowly activating cardiac delayed rectifier current I(Ks), a key regulator of the heart...

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Detalles Bibliográficos
Autores principales: Rinné, Susanne, Oertli, Annemarie, Nagel, Claudia, Tomsits, Philipp, Jenewein, Tina, Kääb, Stefan, Kauferstein, Silke, Loewe, Axel, Beckmann, Britt Maria, Decher, Niels
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865342/
https://www.ncbi.nlm.nih.gov/pubmed/36674868
http://dx.doi.org/10.3390/ijms24021350

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865342/
https://www.ncbi.nlm.nih.gov/pubmed/36674868
http://dx.doi.org/10.3390/ijms24021350

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