Cargando…

Lactone Stabilized by Crosslinked Cyclodextrin Metal-Organic Frameworks to Improve Local Bioavailability of Topotecan in Lung Cancer

The protection of unstable anticancer molecules and their delivery to lesions are challenging issues in cancer treatment. Topotecan (TPT), a classic cytotoxic drug, is widely used for treating refractory lung cancer. However, the therapeutic effects of TPT are jeopardized by its active lactone form...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xiong, Ting, Guo, Tao, He, Yaping, Cao, Zeying, Xu, Huipeng, Wu, Wenting, Wu, Li, Zhu, Weifeng, Zhang, Jiwen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865350/ https://www.ncbi.nlm.nih.gov/pubmed/36678769 http://dx.doi.org/10.3390/pharmaceutics15010142

Ejemplares similares

Simultaneous improvement to solubility and bioavailability of active natural compound isosteviol using cyclodextrin metal-organic frameworks
por: Chen, Xiaojin, et al.
Publicado: (2021)

Oral topotecan: bioavailability and effect of food co-administration
por: Herben, V M M, et al.
Publicado: (1999)

Bioavailability and pharmacokinetics of oral topotecan: a new topoisomerase I inhibitor.
por: Schellens, J. H., et al.
Publicado: (1996)

Dual Inhibition of P-gp and BCRP Improves Oral Topotecan Bioavailability in Rodents
por: Lee, Jaeok, et al.
Publicado: (2021)

Transferrin-Conjugated pH-Responsive γ-Cyclodextrin Nanoparticles for Antitumoral Topotecan Delivery
por: Yoon, Seonyoung, et al.
Publicado: (2020)

Metal-organic frameworks for advanced drug delivery
por: He, Siyu, et al.
Publicado: (2021)

Improvement in the stability and bioavailability of pumpkin lutein using β‐cyclodextrin microcapsules
por: Shi, Zhenxia, et al.
Publicado: (2023)

Cuboidal tethered cyclodextrin frameworks tailored for hemostasis and injured vessel targeting
por: He, Yaping, et al.
Publicado: (2019)

Cyclodextrins Modified/Coated Metal–Organic Frameworks
por: Zhang, Huacheng, et al.
Publicado: (2020)

Cyclodextrin Stabilized Freeze-Dried Silica/Chitosan Nanoparticles for Improved Terconazole Ocular Bioavailability
por: Zaghloul, Nada, et al.
Publicado: (2022)

Andrographis paniculata Formulations: Impact on Diterpene Lactone Oral Bioavailability
por: Loureiro Damasceno, João Paulo, et al.
Publicado: (2021)

Facile stabilization of a cyclodextrin metal–organic framework under humid environment via hydrogen sulfide treatment
por: Ke, Duo, et al.
Publicado: (2019)

Mechanochemical green synthesis of hyper-crosslinked cyclodextrin polymers
por: Rubin Pedrazzo, Alberto, et al.
Publicado: (2020)

Controlled Release of Thymol by Cyclodextrin Metal-Organic Frameworks for Preservation of Cherry Tomatoes
por: Li, Zhicheng, et al.
Publicado: (2022)

Enhancement of Naringenin Bioavailability by Complexation with Hydroxypropoyl-β-Cyclodextrin
por: Shulman, Maria, et al.
Publicado: (2011)

The hydroxypropyl–β-cyclodextrin complexation of toltrazuril for enhancing bioavailability
por: Zhang, Li, et al.
Publicado: (2018)

The Study of Release Mechanisms for Drug in Cyclodextrin Metal–Organic Frameworks
por: Liu, Congbiao, et al.
Publicado: (2019)

Preparation of Crystal Violet Lactone Complex and Its Effect on Discoloration of Metal Surface Coating
por: Li, Wenbo, et al.
Publicado: (2022)

Robust Inclusion Complex of Topotecan Comprised within a Rhodamine-Labeled β-Cyclodextrin: Competing Proton and Energy Transfer Processes
por: Di Nunzio, Maria Rosaria, et al.
Publicado: (2023)

Cholesterol Removal from Whole Egg by Crosslinked β-Cyclodextrin
por: Jeong, H. J., et al.
Publicado: (2014)

Commentary: Periocular topotecan for retinoblastoma
por: Sharma, Minal, et al.
Publicado: (2018)

Metronomic Chemotherapy Based on Topotecan or Topotecan and Cyclophosphamide Combination (CyTo) in Advanced, Pretreated Ovarian Cancer
por: Wysocki, Piotr J., et al.
Publicado: (2023)

Correction: Enhancement of Naringenin Bioavailability by Complexation with Hydroxypropoyl-β-Cyclodextrin
por: Shulman, Maria, et al.
Publicado: (2012)

Enhanced oral bioavailability of fluvastatin by using nanosuspensions containing cyclodextrin
por: Li, Jun, et al.
Publicado: (2018)

Cyclodextrin-Based Metal-Organic Frameworks (CD-MOFs) in Pharmaceutics and Biomedicine
por: Han, Yaoyao, et al.
Publicado: (2018)

Cyclodextrin metal-organic framework as vaccine adjuvants enhances immune responses
por: Li, Congcong, et al.
Publicado: (2021)

Oral Bioavailability of Kinsenoside in Beagle Dogs Measured by LC-MS/MS: Improvement of Ex Vivo Stability of a Lactone-Containing Compound
por: Zhang, Xin, et al.
Publicado: (2018)

Preparation, Characterization, and Bioavailability of Host-Guest Inclusion Complex of Ginsenoside Re with Gamma-Cyclodextrin
por: Li, Hui, et al.
Publicado: (2021)

Weak complexation of 5-fluorouracil with β-cyclodextrin, carbonate, and dianhydride crosslinked β-cyclodextrin: in vitro and in silico studies
por: Mashaqbeh, Hadeia, et al.
Publicado: (2022)

Removal of Volatile Phenols From Wine Using Crosslinked Cyclodextrin Polymers
por: Dang, Chao, et al.
Publicado: (2020)

The Influence of the Hydroxyl Type on Crosslinking Process in Cyclodextrin Based Polyurethane Networks
por: Peptu, Cristian, et al.
Publicado: (2022)

Topotecan and Cyclophosphamide in Adults with Relapsed Sarcoma
por: Blanchette, P., et al.
Publicado: (2012)

Periocular topotecan for vitreous seeds in retinoblastoma
por: Sthapit, Purnima R, et al.
Publicado: (2018)

A Smart Core-Crosslinked Supramolecular Drug Delivery System (SDDS) Enabled by Pendant Cyclodextrins Encapsulation of Drug Dimers via Host-Guest Interaction
por: Xing, Xin, et al.
Publicado: (2021)

Synthesis and potential applications of cyclodextrin-based metal–organic frameworks: a review
por: Xu, Yang, et al.
Publicado: (2022)

γ-Cyclodextrin Metal-Organic Frameworks: Do Solvents Make a Difference?
por: Oh, Jia X., et al.
Publicado: (2023)

Biomimetic mimicry of formaldehyde-induced DNA–protein crosslinks in the confined space of a metal–organic framework
por: Wei, Yu-Bai, et al.
Publicado: (2022)

Antioxidant, Antimicrobial, and Kinetic Studies of Β-Cyclodextrin Crosslinked with Lignin for Drug Delivery
por: Anghel, Narcis, et al.
Publicado: (2022)

Effect of Transglutaminase Pre-Crosslinking Treatment Incorporated with Glucono-δ-lactone on the Physicochemical and Digestive Properties of Tofu
por: Hui, Tianran, et al.
Publicado: (2022)

Bioavailability of an R-α-Lipoic Acid/γ-Cyclodextrin Complex in Healthy Volunteers
por: Ikuta, Naoko, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_183hubmjqb5lsl1baap9l9p8da