The Effect of the Particle Size Reduction on the Biorelevant Solubility and Dissolution of Poorly Soluble Drugs with Different Acid-Base Character

Particle size reduction is a commonly used process to improve the solubility and the dissolution of drug formulations. The solubility of a drug in the gastrointestinal tract is a crucial parameter, because it can greatly influence the bioavailability. This work provides a comprehensive investigation...

Descripción completa

Detalles Bibliográficos
Autores principales: Csicsák, Dóra, Szolláth, Rita, Kádár, Szabina, Ambrus, Rita, Bartos, Csilla, Balogh, Emese, Antal, István, Köteles, István, Tőzsér, Petra, Bárdos, Vivien, Horváth, Péter, Borbás, Enikő, Takács-Novák, Krisztina, Sinkó, Bálint, Völgyi, Gergely
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865396/
https://www.ncbi.nlm.nih.gov/pubmed/36678907
http://dx.doi.org/10.3390/pharmaceutics15010278

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865396/
https://www.ncbi.nlm.nih.gov/pubmed/36678907
http://dx.doi.org/10.3390/pharmaceutics15010278

Ejemplares similares