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Ca(2+) Homeostasis by Plasma Membrane Ca(2+) ATPase (PMCA) 1 Is Essential for the Development of DP Thymocytes

The strength of Ca(2+) signaling is a hallmark of T cell activation, yet the role of Ca(2+) homeostasis in developing T cells before expressing a mature T cell receptor is poorly understood. We aimed to unveil specific functions of the two plasma membrane Ca(2+) ATPases expressed in T cells, PMCA1 a...

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Detalles Bibliográficos
Autores principales: Beckmann, David, Langnaese, Kristina, Gottfried, Anna, Hradsky, Johannes, Tedford, Kerry, Tiwari, Nikhil, Thomas, Ulrich, Fischer, Klaus-Dieter, Korthals, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865543/
https://www.ncbi.nlm.nih.gov/pubmed/36674959
http://dx.doi.org/10.3390/ijms24021442