Synthesis and Evaluation of Novel S-alkyl Phthalimide- and S-benzyl-oxadiazole-quinoline Hybrids as Inhibitors of Monoamine Oxidase and Acetylcholinesterase

New S-alkyl phthalimide 5a–f and S-benzyl 6a–d analogs of 5-(2-phenylquinolin-4-yl)-1,3,4-oxadiazole-2-thiol (4) were prepared by reacting 4 with N-bromoalkylphthalimide and CF(3)-substituted benzyl bromides in excellent yields. Spectroscopic techniques were employed to elucidate the structures of t...

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Detalles Bibliográficos
Autores principales: Khan, Bilal Ahmad, Hamdani, Syeda Shamila, Jalil, Saquib, Ejaz, Syeda Abida, Iqbal, Jamshed, Shawky, Ahmed M., Alqahtani, Alaa M., Gabr, Gamal A., Ibrahim, Mahmoud A. A., Sidhom, Peter A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865589/
https://www.ncbi.nlm.nih.gov/pubmed/36678507
http://dx.doi.org/10.3390/ph16010011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865589/
https://www.ncbi.nlm.nih.gov/pubmed/36678507
http://dx.doi.org/10.3390/ph16010011

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