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Polyploid/Multinucleated Giant and Slow-Cycling Cancer Cell Enrichment in Response to X-ray Irradiation of Human Glioblastoma Multiforme Cells Differing in Radioresistance and TP53/PTEN Status

Radioresistance compromises the efficacy of radiotherapy for glioblastoma multiforme (GBM), the most devastating and common brain tumor. The present study investigated the relationship between radiation tolerance and formation of polyploid/multinucleated giant (PGCC/MGCC) and quiescent/senescent slo...

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Detalles Bibliográficos
Autores principales: Alhaddad, Lina, Chuprov-Netochin, Roman, Pustovalova, Margarita, Osipov, Andreyan N., Leonov, Sergey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865596/
https://www.ncbi.nlm.nih.gov/pubmed/36674747
http://dx.doi.org/10.3390/ijms24021228