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A Mutation in Mouse MT-ATP6 Gene Induces Respiration Defects and Opposed Effects on the Cell Tumorigenic Phenotype

As the last step of the OXPHOS system, mitochondrial ATP synthase (or complex V) is responsible for ATP production by using the generated proton gradient, but also has an impact on other important functions linked to this system. Mutations either in complex V structural subunits, especially in mtDNA...

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Detalles Bibliográficos
Autores principales: Moreno-Loshuertos, Raquel, Movilla, Nieves, Marco-Brualla, Joaquín, Soler-Agesta, Ruth, Ferreira, Patricia, Enríquez, José Antonio, Fernández-Silva, Patricio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865613/
https://www.ncbi.nlm.nih.gov/pubmed/36674816
http://dx.doi.org/10.3390/ijms24021300