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A Mutation in Mouse MT-ATP6 Gene Induces Respiration Defects and Opposed Effects on the Cell Tumorigenic Phenotype
As the last step of the OXPHOS system, mitochondrial ATP synthase (or complex V) is responsible for ATP production by using the generated proton gradient, but also has an impact on other important functions linked to this system. Mutations either in complex V structural subunits, especially in mtDNA...
Autores principales: | Moreno-Loshuertos, Raquel, Movilla, Nieves, Marco-Brualla, Joaquín, Soler-Agesta, Ruth, Ferreira, Patricia, Enríquez, José Antonio, Fernández-Silva, Patricio |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865613/ https://www.ncbi.nlm.nih.gov/pubmed/36674816 http://dx.doi.org/10.3390/ijms24021300 |
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