Cargando…

Identification of Novel Pathways Regulated by APE1/Ref-1 in Human Retinal Endothelial Cells

APE1/Ref-1 (apurinic/apyrimidinic endonuclease 1, APE1 or APEX1; redox factor-1, Ref-1) is a dual-functional enzyme with crucial roles in DNA repair, reduction/oxidation (redox) signaling, and RNA processing and metabolism. The redox function of Ref-1 regulates several transcription factors, such as...

Descripción completa

Detalles Bibliográficos
Autores principales: Mijit, Mahmut, Liu, Sheng, Sishtla, Kamakshi, Hartman, Gabriella D., Wan, Jun, Corson, Timothy W., Kelley, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865623/
https://www.ncbi.nlm.nih.gov/pubmed/36674619
http://dx.doi.org/10.3390/ijms24021101