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Identification of Novel Pathways Regulated by APE1/Ref-1 in Human Retinal Endothelial Cells
APE1/Ref-1 (apurinic/apyrimidinic endonuclease 1, APE1 or APEX1; redox factor-1, Ref-1) is a dual-functional enzyme with crucial roles in DNA repair, reduction/oxidation (redox) signaling, and RNA processing and metabolism. The redox function of Ref-1 regulates several transcription factors, such as...
Autores principales: | Mijit, Mahmut, Liu, Sheng, Sishtla, Kamakshi, Hartman, Gabriella D., Wan, Jun, Corson, Timothy W., Kelley, Mark R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865623/ https://www.ncbi.nlm.nih.gov/pubmed/36674619 http://dx.doi.org/10.3390/ijms24021101 |
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