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HOXB9 Overexpression Confers Chemoresistance to Ovarian Cancer Cells by Inducing ERCC-1, MRP-2, and XIAP

The purpose of this study was to identify the role of HOXB9 and associated molecular mechanism in acquiring chemoresistance to ovarian cancer cells. After establishing HOXB9-overexpressing cells (HOXB9-OE/SKOV3), cisplatin resistance-induced cells (Cis-R/SKOV3), and an ovarian cancer xenograft mouse...

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Detalles Bibliográficos
Autores principales: Suh, Dong Hoon, Park, Wook Ha, Kim, Miseon, Kim, Kidong, No, Jae Hong, Kim, Yong Beom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865712/
https://www.ncbi.nlm.nih.gov/pubmed/36674764
http://dx.doi.org/10.3390/ijms24021249