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Design and Synthesis of (Z)-2-(Benzylamino)-5-benzylidenethiazol-4(5H)-one Derivatives as Tyrosinase Inhibitors and Their Anti-Melanogenic and Antioxidant Effects

In this study, (Z)-2-(benzylamino)-5-benzylidenethiazol-4(5H)-one (BABT) derivatives were designed as tyrosinase inhibitors based on the structure of MHY2081, using a simplified approach. Of the 14 BABT derivatives synthesized, two derivatives ((Z)-2-(benzylamino)-5-(3-hydroxy-4-methoxybenzylidene)t...

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Detalles Bibliográficos
Autores principales: Lee, Jieun, Park, Yu Jung, Jung, Hee Jin, Ullah, Sultan, Yoon, Dahye, Jeong, Yeongmu, Kim, Ga Young, Kang, Min Kyung, Kang, Dongwan, Park, Yujin, Chun, Pusoon, Chung, Hae Young, Moon, Hyung Ryong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865752/
https://www.ncbi.nlm.nih.gov/pubmed/36677908
http://dx.doi.org/10.3390/molecules28020848