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mtUPR Modulation as a Therapeutic Target for Primary and Secondary Mitochondrial Diseases

Mitochondrial dysfunction is a key pathological event in many diseases. Its role in energy production, calcium homeostasis, apoptosis regulation, and reactive oxygen species (ROS) balance render mitochondria essential for cell survival and fitness. However, there are no effective treatments for most...

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Detalles Bibliográficos
Autores principales: Cilleros-Holgado, Paula, Gómez-Fernández, David, Piñero-Pérez, Rocío, Reche-López, Diana, Álvarez-Córdoba, Mónica, Munuera-Cabeza, Manuel, Talaverón-Rey, Marta, Povea-Cabello, Suleva, Suárez-Carrillo, Alejandra, Romero-González, Ana, Suárez-Rivero, Juan Miguel, Romero-Domínguez, Jose Manuel, Sánchez-Alcázar, Jose Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865803/
https://www.ncbi.nlm.nih.gov/pubmed/36674998
http://dx.doi.org/10.3390/ijms24021482