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Synthesis and Antiparasitic Activity of New Trithiolato-Bridged Dinuclear Ruthenium(II)-arene-carbohydrate Conjugates

Eight novel carbohydrate-tethered trithiolato dinuclear ruthenium(II)-arene complexes were synthesized using CuAAC ‘click’ (Cu(I)-catalyzed azide-alkyne cycloaddition) reactions, and there in vitro activity against transgenic T. gondii tachyzoites constitutively expressing β-galactosidase (T. gondii...

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Detalles Bibliográficos
Autores principales: Holzer, Isabelle, Desiatkina, Oksana, Anghel, Nicoleta, Johns, Serena K., Boubaker, Ghalia, Hemphill, Andrew, Furrer, Julien, Păunescu, Emilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865825/
https://www.ncbi.nlm.nih.gov/pubmed/36677958
http://dx.doi.org/10.3390/molecules28020902