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Increased Proteoglycanases in Pulmonary Valves after Birth Correlate with Extracellular Matrix Maturation and Valve Sculpting

Increased mechanical forces on developing cardiac valves drive formation of the highly organized extracellular matrix (ECM) providing tissue integrity and promoting cell behavior and signaling. However, the ability to investigate the response of cardiac valve cells to increased mechanical forces is...

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Detalles Bibliográficos
Autores principales: Dupuis, Loren E., Evins, Sarah E., Abell, Morgan C., Blakley, Morgan E., Horkey, Samuel L., Barth, Jeremy L., Kern, Christine B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865826/
https://www.ncbi.nlm.nih.gov/pubmed/36661922
http://dx.doi.org/10.3390/jcdd10010027