The Important Role of Membrane Fluidity on the Lytic Mechanism of the α-Pore-Forming Toxin Sticholysin I

Actinoporins have emerged as archetypal α-pore-forming toxins (PFTs) that promote the formation of pores in membranes upon oligomerization and insertion of an α-helix pore-forming domain in the bilayer. These proteins have been used as active components of immunotoxins, therefore, understanding thei...

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Detalles Bibliográficos
Autores principales: Pedrera, Lohans, Ros, Uris, Fanani, Maria Laura, Lanio, María E., Epand, Richard M., García-Sáez, Ana J., Álvarez, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865829/
https://www.ncbi.nlm.nih.gov/pubmed/36668899
http://dx.doi.org/10.3390/toxins15010080

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865829/
https://www.ncbi.nlm.nih.gov/pubmed/36668899
http://dx.doi.org/10.3390/toxins15010080

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