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Optimized Antimicrobial Peptide Jelleine-I Derivative Br-J-I Inhibits Fusobacterium Nucleatum to Suppress Colorectal Cancer Progression

Colorectal cancer (CRC) is a major health burden worldwide due to its high morbidity, mortality, and complex etiology. Fusobacterium nucleatum (Fn), a Gram-negative anaerobe found in 30% of CRC patients, promotes CRC carcinogenesis, metastasis, and chemoresistance. Effective antimicrobial treatment...

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Detalles Bibliográficos
Autores principales: Jia, Fengjing, Yu, Qun, Wang, Ruolei, Zhao, Ling, Yuan, Fuwen, Guo, Haidong, Shen, Yunhui, He, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865857/
https://www.ncbi.nlm.nih.gov/pubmed/36674985
http://dx.doi.org/10.3390/ijms24021469