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Pharmacokinetic/Pharmacodynamic Evaluation of Aztreonam/Amoxicillin/Clavulanate Combination against New Delhi Metallo-β-Lactamase and Serine-β-Lactamase Co-Producing Escherichia coli and Klebsiella pneumoniae

This study aimed to examine specific niches and usage for the aztreonam/amoxicillin/clavulanate combination and to use population pharmacokinetic simulations of clinical dosing regimens to predict the impact of this combination on restricting mutant selection. The in vitro susceptibility of 19 New-D...

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Detalles Bibliográficos
Autores principales: Zhang, Jiayuan, Wu, Mengyuan, Diao, Shuo, Zhu, Shixing, Song, Chu, Yue, Jiali, Martins, Frederico S., Zhu, Peijuan, Lv, Zhihua, Zhu, Yuanqi, Yu, Mingming, Sy, Sherwin K. B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9865866/
https://www.ncbi.nlm.nih.gov/pubmed/36678879
http://dx.doi.org/10.3390/pharmaceutics15010251